COVID-19 Preoperative Blood Tests : What Do They Tell Us About COVID-19 Vaccines ?

Abstract

This observational real-world study was conducted on 14 patients who needed a minor office surgery or procedure and who were eligible for a COVID-19 booster according to the French Health Agency. The aim of the study was focused on biological markers which might have an incidence after surgery. The platelet count, D-dimer level, and anti-spike IgG antibodies levels, were the numeric parameters studied. The study showed no perturbation in the platelet count. Conversely, we observed an abnormal elevation of D-dimer levels in 4 patients (28 %). The most remarkable data was the constant residual positive level anti-spike IgG antibodies observed in all patients after 6 months ranging from 44 to 5680 BAU/mL. For these reasons, further studies on a bigger cohort would be useful to clarify the possible incidence of COVID-19 vaccines on D-dimer levels and a monitoring of the immune response should be proposed to all patients eligible for a SARS-CoV-2 vaccine booster in order to evaluate the benefit-risk ratio of this injection.