A case report of active surveillance therapy: Citrus-peel extracts’ efficacy against prostate cancer

Authors

  • Shinji Kageyama Kageyama Urology Clinic, Shizuoka, Japan
  • Shinsuke Hayami Department of Urology, Fujieda City General Hosipital, Shizuoka, Japan
  • Seiji Ohmura Ohmura Clinic, Gifu, Japan
  • Michiko Suzawa Miyauchi Citrus Laboratories, Gunma, Japan
  • Shizuo Yamada Center of Pharma-Food Reseach, Shizuoka University, Shizuoka, Japan

Keywords:

Active Surveillance, complementary or alternative -medicine (CAM), Gold Lotion, nobiletin, polymethoxyflavones

Abstract

Active surveillance therapy (AS), patients feel uneasiness about not taking any conventional
medications. Sixty one years old man was diagnosed with prostate cancer at the clinical stage of
T2aNoMo with Gleason 3+4 and PSA of 6.4 ng/mL. This patient chose AS. Nine years later, his PSA
value gradually increased to over 10 ng/mL. Although the PSA level was rising, Magnetic resonance
imaging (MRI) examination did not indicate obvious abnormal lesions. The patient heard about Gold
Lotion (GL) by word of mouth and was willing to try it out on him. After drinking GL, MRI showed no
abnormal results. He received another biopsy, and collected specimens showed G3+4. He continued
with AS with GL and his PSA value remained less than 11 ng/mL for about 4 years. In some limited
cases, the addition of GL drinking to AS can be considered as an effective method to eliminate
patients’ anxiety (145 wards).

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Published

2022-04-03

Issue

In_Press

Section

Articles