Efficacies of two medicinal plants [Goma Guar Walmart (Cyamopsis tetragonolobus L.) and Cinnamon (Cinnamomum verum)] versus efficacy of allopathic treatment [Sil–Norboral (Glibenclamide 5 mg/Metformin 1000 mg plus Janumet (Sitagliptin 50 mg/Metformin 850

Abstract

The objective of this study was to statistically compare –using the One–Way Analysis of Variance and
Dunnett's multiple comparisons test– the efficacy of Cyamopsis tetragonolobus L. and Cinnamomum
verum versus the efficacy of the allopathic treatment Sil–Norboral (Glibenclamide 5 mg/Metformin
1000 mg) + Janumet (Sitagliptin 50 mg/Metformin 850 mg) as hypoglycemic agents in patients with
type 2 diabetes mellitus who attend the "Dr. Agustin O'Horán" General Hospital for medical care. The
epistemological approach is quantitative, probabilistic or positivistic. The study design corresponds to
that of a therapeutic experimental epidemiological study (therapeutic clinical trial) with prospective
temporality. Forty–eight patients with type 2 diabetes mellitus were studied. The 48 patients were
randomly assigned to three groups: two experimental groups and one control group. Each group was
made up of 16 patients. The first experimental group was given Cyamopsis tetragonolobus L. (twelve
dry leaves of Cyamopsis tetragonolobus L. and 500 ml of hot water); pour the 500 ml of hot water into a
container and add the twelve dry leaves of Cyamopsis tetragonolobus L.; take 250 ml in the morning and
250 ml at night); the second experimental group was given Cinnamomum verum (two g of dry leaves of
Cinnamomum verum and 500 ml of hot water; pour the 500 ml of hot water into a container and add two
g of dry leaves of Cinnamomum verum; take 250 ml in the morning and 250 ml at night); and the control
group was given the Sil–Norboral allopathic treatment (Glibenclamide 5 mg/Metformin 1000 mg) +
Janumet (Sitagliptin 50 mg/Metformin 850 mg). In ascending numerical order, the arithmetic means
of the hematic glucose values corresponded to the following treatments: Cyamopsis tetragonolobus L.
(84.06 mg/100mL); Cinnamomum verum (88.63mg/100mL); and Sil–Norboral (Glibenclamide 5 mg/
Metformin 1000 mg) + Janumet (Sitagliptin 50 mg/Metformin 850 mg) (122.25 mg/100mL). The One–
Way Analysis of Variance reported a value of F= 56.03 with a value of p= 0.0000, which indicates a
statistically significant difference between a pair or between more than one pair of arithmetic means.
Dunnett's multiple comparisons test showed statistically significant differences between the treatment
with the medicinal plant Cyamopsis tetragonolobus L. and the allopathic treatment Sil–Norboral +
Janumet: p= 0000. Likewise, Dunnett's multiple comparisons test showed a statistically significant
difference between the treatment with the medicinal plant Cinnamomum verum and the allopathic
treatment Sil–Norboral + Janumet: p= 0.0000. It is concluded that Cyamopsis tetragonolobus L. is, from
a numerical and not a statistical point of view, the best hypoglycemic agent for the treatment of type 2
diabetes mellitus.