Treatment of cutaneous photoaging lesions with autologous platelet concentrate

Abstract

Background: Facial aging causes a devastating physical and mental impact on quality of life.
Objective: To evaluate the efficacy and safety of autologous platelet concentrate (APC) in the treatment
of cutaneous photoaging (SCF).

Method: Between March 1, 2017 and March 31, 2021, at the “Hermanos Ameijeiras” hospital, a
randomized, single-center, double-blind and controlled clinical trial was carried out in 164 patients with
ECF. A group treated with CPA was compared to another treated with fresh autologous plasma (AFP).
The treatment was applied monthly for 1 year.

Results: Three months after the end of the treatment, there were significant differences between the
patients treated with CPA compared to those treated with PFA in terms of the improvement in the degree
of photodamage and the degree of satisfaction (p <0.001). All adverse events were of mild intensity, did
not imply changes before the intervention and were completely resolved.

Conclusions: The autologous platelet concentrate proved to be effective and safe to reduce the signs of
skin aging, associated with a high degree of patient satisfaction.