Treatment With Vaginal Oxygen Therapy in Patients With Genitourinary Syndrome of Menopause Symptoms: An Observational Trial

Authors

  • Filippo Murina Lower Genital Tract Disease Unit, V. Buzzi Hospital–University of the Study of Milan, Milan, Italy
  • Dario Recalcati Lower Genital Tract Disease Unit, V. Buzzi Hospital–University of the Study of Milan, Milan, Italy
  • Stefania Di Francesco Lower Genital Tract Disease Unit, V. Buzzi Hospital–University of the Study of Milan, Milan, Italy

Abstract

Genitourinary Syndrome of Menopause (GSM) GSM is a chronic and progressive condition
that can have many medical consequences (vaginal dryness, vulvar pain, dyspareunia, and
dysuria) that may affect quality of life. The objective of our study was to evaluate the efficacy
of vaginal hyperbaric oxygen treatment on GSM. Thirty patients received six weekly sessions
of 95% pure oxygen that was delivered at a flow of 2 lt/ minute for 15 minutes using a cannula
designed for vaginal therapy, with a subsequent follow-up after two months. There was a
significant improvement in vaginal dryness (before treatment VAS 7.52 versus 3.52 after
treatment -p = 0.05). The same improvement was observed for vulvar burning/pain and
dyspareunia, but these were not statistically significant. VHI before treatment was 15.1 versus
19.59 after treatment (p = 0.05). All the parameters maintain their value at 2 months of
follow-up. No adverse effects were observed.

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Published

2022-12-23

Issue

Vol. 2 No. 2: Current Issue

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Articles