NEURON ON: A Bioactive Moringa Oil Targeting Oxidative Stress and Silent Synapses in Neurological Disorders Including Epilepsy

Authors

  • Cruz-Rodriguez L Elidan Bioactive Compounds LLC, Tampa, FL, USA Author
  • Carrasco A Neurology & Pain Medicine: 14201 SW 120th St suite 109, Miami, FL 33186, USA Author
  • Garcia CM Elidan Bioactive Compounds LLC, Tampa, FL, USA Author
  • Angomas A Oxygen TherapyRD, Hotel Here suites. Dominican Republic Author
  • Martinez E University of Alabama at Birmingham, AL, USA Author
  • Valle-Orta M National Graphene Materials Laboratory, Center for Research in Applied Chemistry (CIQA) in Saltillo, Mexico, Author
  • Rosales-Castro I Kendall South Medical Center, FL, USA Author
  • Dans EA Kendall South Medical Center, FL, USA Author

DOI:

https://doi.org/10.33425/2692-7918.1099

Keywords:

Nuclear medicine, PET

Abstract

Recent research into neuronal regeneration for epilepsy has focused on silent, or passive, synapses— synaptic junctions that are anatomically present but electrically inactive. These synapses may serve as potential sites for reactivation and neuronal recovery, especially following injury or disease. "NEURON ON," a novel bioactive moringa oil formulation enriched with CBD and delivered via exogenous exosomes, aims to reduce oxidative stress and reawaken silent synapses. In a proof-of-concept trial, 243 patients with epilepsy (ages 25–75) received personalized sublingual doses of NEURON ON. The oxidative stress coefficient (OSC) was measured using the LONGLIFE OXY-LORD (LLOL) calculator. Results demonstrated that 198 participants (81.48%) showed a 50% reduction in OSC, corresponding to a 90% oxidative stress relief rate. Additionally, patients exhibited an average 12% reduction in estimated biological age. These findings suggest that NEURON ON may promote neuronal regeneration by forming a melanin-like lipid interface that facilitates connectivity among low-activity neurons. Given these outcomes, EEG evaluations are recommended to validate functional neural recovery. NEURON ON holds promise as a personalized oxidative stress-reducing therapy for epilepsy and other oxidative pathologies affecting neuronal connectivity

Published

2025-08-01

Issue

Section

Articles