Incidences of Hepatitis-B Within Kirkuk Province in Iraq, a Biochemical Study of Some Liver Enzymes

Abstract

Geographical distribution of Hepatitis-B, both acute and chronic caused by the hepatitis-B virus (HBV) has always been attracting attention worldwide. Prevalence of HBV does vary among genders and ages while symptomatic and asymptomatic are not uncommon. The present research involved assessment of three different parameters i.e. four liver enzymes, hematological and serological factors in 91 patients (70 male and 21 female) compared with 28 control counterpart (23 male and 5 female) admitted a private Medical laboratory in Kirkuk province. The arithmetic values of the 4 main liver enzymes, Alanine Trans-Aminase (ALT), Alkaline phosphatase (ALP); aspartate transaminase (AST) and GammaGlutamyl transferase (GGT) showed significant increase (p≤0.05-0.001) in Hepatitis-B patients in comparison with their counterpart healthy individuals. An insignificant differences was detectable in both WBC and Hb% values meanwhile significant increases (20-25 folds) elevation was detected in the total serum bilirubin (TSB) of HBV patients. Variations in the values of these enzymes, particularly ALT enzyme, was also prominent between the genders e.g. in male patients were comparable with their counterparts female. The values of the enzyme ALT, particularly in female hepatitis, were four folds higher than males; however, other enzyme showed lesser value variations ranged between significant to insignificant. It is conclude that regular check-up of these enzymes deems necessary for personal health purposes of HBV patients.