Pattern of dyslipidaemia in coronary artery disease in south-South Nigeria

Abstract

Introduction: Dyslipidemia is an independent traditional risk factor for coronary artery disease (CAD). The pattern of dyslipidemia and coronary artery disease among sub-Saharan Africans has not been widely studied. Hence, this study was conducted with the objective to evaluate pattern of lipid abnormalities in patients with established coronary artery disease. Methods: It was a prospective study of the pattern of dyslipidemia among patients with established coronary artery disease from angiographic diagnosis. All patients with dyslipidemia who had coronary angiography were evaluated for pattern of lipid profile. Results: There were a total of 65 subjects with age ranging from 35 to 85 years (Male: 34; Female: 31). The mean age of participants was 62.1 ± 12.0 years. There were more subjects with mixed (combined) dyslipidemia who had significant coronary artery disease compared with isolated dyslipidemia (p-value <0.001). There was no significant difference between the male and female with dyslipidemia. The mean values of total cholesterol, low density lipoprotein and triglycerides were higher among the subjects with dyslipidemia. Conclusion: The study showed that combined dyslipidemia is commonly seen in patients with coronary artery disease as compared with isolated dyslipidemia.