Posterior capsule opacification (PCO) rate of a hydrophilic acrylic intraocular lens suitable for microincisional cataract surgery (MICS)

Abstract

Purpose: To determine the capsulotomy rate of MICS-IOL (IntraOcular Lens) L-313 compared to other IOLs.
Setting: Department of Ophthalmology of the Dietrich Bonhoeffer Klinikum (DBK) in Neubrandenburg, Germany, Teaching Hospital of the University Greifswald, Germany
Design: Monocentric, partly retrospective and partly prospective study
Method: Data from a total of 5.549 eyes implanted with MICS IOL LENTIS L-313 (OSD Medical GmbH, Berlin, Germany) during cataract surgery in our clinic between 9/2009 and 12/2013 were collected between 5/2013 and 10/2017. It is registered at www.clinicaltrials.gov (NCT03184428).
The performance of a laser capsulotomy was evaluated as a criterion for the presence of a clinically relevant PCO. The statistical evaluation was carried out using Kaplan-Meier statistics with the program STATISTICA, Version 13 (StatSoft, Hamburg, Germany).
Results: The average patient age was 73.75 years ± 9.06 (range 5 to 96) and 59.2% were female. The median follow-up period is 4.2 years. 4.224 data sets could be evaluated for patients over 54 years of age.
The IOL L-313 PCO rate is 4.7% after 1 year, 8.2% after 2 years, 17.2% after 4 years and 22.4% after 6 years. The L-313's PCO rate is low compared to other MICS lenses and two to three times higher compared to non-MICS lenses with a sharp optical edge. It is only half compared to that of (PMMA) lenses. Conclusions: The L-313 IOL's PCO rate is approximately twice to three times higher than non-MICS IOLs with a sharp optical edge but low compared to the PCO rate of other MICS-IOLs.