Rhabdomyolysis in a Physically Active Patient on Isotretinoin Therapy: A Case Report

Abstract

Isotretinoin therapy remains the therapeutic resort when all other treatments for acne have failed, however it is accompanied by a high side-effect profile. Isotretinoin-induced muscle injuries have been associated with markedly elevated creatine kinase (CK) in multiple reports in the literature. We report the case of a 36 year-old female on isotretinoin therapy for intractable acne who developed generalized myalgia one day subsequent to a strenuous workout at the gym