Hormonal Imbalances and Obsessive-Compulsive Disorder

Abstract

Obsessive-compulsive disorder (OCD) is a chronic mental health condition marked by intrusive thoughts and repetitive behaviors, significantly impairing daily functioning. This paper investigates the relationship between hormonal imbalances and OCD by reviewing existing literature and presenting detailed case studies. The analysis focuses on the impact of hormonal fluctuations, particularly involving estrogen, androgens, progesterone, melatonin, and cortisol, on the onset and severity of OCD symptoms. Case studies of individuals with polycystic ovary syndrome (PCOS), postpartum hormonal changes, and post-hysterectomy hormonal shifts illustrate how hormonal imbalances can exacerbate OCD symptoms. The findings indicate that hormonal events, such as premenstrual periods and pregnancy, can trigger or worsen OCD symptoms in approximately 30% of women. Hormone replacement therapy and targeted hormonal interventions show promise in alleviating OCD symptoms, suggesting a potential for hormonebased treatment approaches. This study underscores the need for a comprehensive understanding of hormonal influences in managing OCD to enhance treatment outcomes and improve patients' quality of life.